5-三磷酸肌醇受体2抗体
交货期:1周
产品别名:肌醇-1,3,4-三磷酸受体2(ITPR2)抗体
Anti-ITPR2
靶标:
ITPR2
产品别名:
ANHD; CFAP48; INSP3R2; IP3R2; ITPR2; inositol 1,4,5-trisphosphate receptor type 2; inositol 1,4,5-trisphosphate receptor type 2; inositol 1,4,5-trisphosphate receptor type 2; IP3 receptor; IP3R 2; cilia and flagella associated protein 48; type 2 InsP3 receptor; 5-三磷酸肌醇受体2; 肌醇-1,3,4-三磷酸受体2(ITPR2);
背景信息:
The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
产品发布日期:2026.01.29