TCFL5抗体
交货期:1周
产品别名:Anti-TCFL5
Anti-transcription factor like 5 Antibody
靶标:
TCFL5
产品别名:
CHA; E2BP-1; Figlb; SOSF1; bHLHe82; TCFL5; transcription factor like 5; transcription factor like 5; transcription factor-like 5 protein; HPV-16 E2-binding protein 1; cha transcription factor; spermatogenesis- and oogenesis-specific bHLH-containing protein 1; transcription factor-like 5 (basic helix-loop-helix);
背景信息:
developmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,
产品发布日期:2026.03.23