IQSEC2抗体
交货期：1周
产品别名：Anti-IQSEC2
Anti-IQ motif and Sec7 domain ArfGEF 2 Antibody
Anti-IQ motif and Sec7 domain ArfGEF 2 Antibody
靶标：
产品别名：
背景信息：
IQSEC2
产品别名：
BRAG1； IQ-ArfGEF； MRX1； MRX18； MRX78； XLID1； IQSEC2； IQ motif and Sec7 domain ArfGEF 2； IQ motif and Sec7 domain ArfGEF 2； IQ motif and SEC7 domain-containing protein 2； IQ motif and Sec7 domain 2； brefeldin A resistant Arf-guanine nucleotide exchange factor 1； brefeldin A resistant Arf-guanine nucleotide exchange factor 1b； brefeldin A resistant Arf-guanine nucleotide exchange factor 1c；
背景信息：
IQSEC2 is a 1,478 amino acid protein that belongs to the BRAG family and contains one IQ domain, one PH domain and a SEC7 domain. Localizing to the cytoplasm, IQSEC2 is expressed in brain, kidney and small intestine, with weaker levels of expression in placenta, pancreas, ovary, prostate and liver. IQSEC2 is a component of the postsynaptic density at excitatory synapses, and interacts with ARF family members as a guanine nucleotide exchange factor. Through the activation of ARF substrates, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization. The gene encoding IQSEC2 maps to the human X chromosome. Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), a condition characterized by decreased intellectual function. IQSEC2 exists as three isoforms due to alternative splicing events.
产品发布日期：2026.01.24
广州伟伯科技有限公司