广州伟伯科技有限公司
环指蛋白186抗体

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交货期:1周
产品别名:Anti-RNF186
Anti-ring finger protein 186 Antibody
靶标:

RNF186


产品别名:

RNF186; ring finger protein 186; ring finger protein 186; E3 ubiquitin-protein ligase RNF186; 环指蛋白186;


背景信息:
RNF186 is an E3 ubiquitin ligase that regulates endoplasmic reticulum (ER) stress and apoptosis through its interaction with BNIP1. This gene is mapped to chromosome 1p36.13 based on an alignment of theRNF186 sequence with the genomic sequence (GRCh38). Cotransfection and immunoprecipitation analyses showed that RNF186, through it transmembrane domains, interacted with BNIP1. Overexpression of RNF186 promoted BNIP1 ubiquitination and transfer of BNIP1 to mitochondria.
产品发布日期:2026.01.26
广州伟伯科技有限公司