ATP依赖RNA解旋酶DDX60抗体
交货期：1周
产品别名：Anti-DDX60
Anti-DExD/H-box helicase 60 Antibody
Anti-DExD/H-box helicase 60 Antibody
靶标：
产品别名：
背景信息：
DDX60
产品别名：
DDX60； DExD/H-box helicase 60； DExD/H-box helicase 60； probable ATP-dependent RNA helicase DDX60； ATP-dependent RNA helicase DDX60； DEAD (Asp-Glu-Ala-Asp) box polypeptide 60； DEAD box protein 60； DEAD-box helicase 60； ATP依赖RNA解旋酶DDX60；
背景信息：
DDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
产品发布日期：2026.03.20
广州伟伯科技有限公司