FBXL20蛋白抗体
交货期：1周
产品别名：Anti-Fbxl20
Anti-F-box and leucine-rich repeat protein 20 Antibody
Anti-F-box and leucine-rich repeat protein 20 Antibody
靶标：
产品别名：
背景信息：
Fbxl20
产品别名：
Fbl2； Fbxl2； Fbxl20； F-box and leucine-rich repeat protein 20； F-box and leucine-rich repeat protein 20； F-box/LRR-repeat protein 20； F-box protein FBL2； FBXL20蛋白；
背景信息：
Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
产品发布日期：2026.03.23
广州伟伯科技有限公司