G蛋白信号转导调节因子18抗体
交货期:1周
产品别名:Anti-Rgs18
Anti-regulator of G-protein signaling 18 Antibody
靶标:
Rgs18
产品别名:
Rgs18; regulator of G-protein signaling 18; regulator of G-protein signaling 18; G蛋白信号转导调节因子18;
背景信息:
Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
产品发布日期:2026.01.24