新型血小板相关血管内皮分泌蛋白SCUBE1抗体
交货期：1周
产品别名：Anti-Scube1
Anti-signal peptide, CUB domain, EGF-like 1 Antibody
Anti-signal peptide, CUB domain, EGF-like 1 Antibody
靶标：
产品别名：
背景信息：
Scube1
产品别名：
7330410C13Rik； A630023E24Rik； Scube1； signal peptide, CUB domain, EGF-like 1； signal peptide, CUB domain, EGF-like 1； signal peptide, CUB and EGF-like domain-containing protein 1； 新型血小板相关血管内皮分泌蛋白SCUBE1；
背景信息：
SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
产品发布日期：2026.03.20
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