E1A样分化抑制因子3抗体
交货期:1周
产品别名:Anti-Eid3
Anti-EP300 interacting inhibitor of differentiation 3 Antibody
靶标:
Eid3
产品别名:
1700027M21Rik; NS4EB; Eid3; EP300 interacting inhibitor of differentiation 3; EP300 interacting inhibitor of differentiation 3; EP300-interacting inhibitor of differentiation 3; EID-1-like inhibitor of differentiation 3; non-SMC element 4 homolog B; non-structural maintenance of chromosomes element 4 homolog B; E1A样分化抑制因子3;
背景信息:
EID3?is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
产品发布日期:2026.01.24