广州伟伯科技有限公司
锌指蛋白结构域ZFYVE21抗体

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交货期:1周
产品别名:Anti-Zfyve21
Anti-zinc finger, FYVE domain containing 21 Antibody
靶标:

Zfyve21


产品别名:

1110013H04Rik; AW558780; C85416; Zfyve21; zinc finger, FYVE domain containing 21; zinc finger, FYVE domain containing 21; zinc finger FYVE domain-containing protein 21; 锌指蛋白结构域ZFYVE21;


背景信息:
ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
产品发布日期:2025.08.07
广州伟伯科技有限公司