FOXRED2蛋白抗体
交货期：1周
产品别名：Anti-FOXRED2
Anti-FAD dependent oxidoreductase domain containing 2 Antibody
Anti-FAD dependent oxidoreductase domain containing 2 Antibody
靶标：
产品别名：
背景信息：
FOXRED2
产品别名：
ERFAD； FOXRED2； FAD dependent oxidoreductase domain containing 2； FAD dependent oxidoreductase domain containing 2； FAD-dependent oxidoreductase domain-containing protein 2； ER flavoprotein associated with degradation； endoplasmic reticulum flavoprotein associated with degradation； FOXRED2蛋白；
背景信息：
FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
产品发布日期：2026.01.29
广州伟伯科技有限公司