广州伟伯科技有限公司
14号染色体开放阅读框146抗体

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交货期:1周
产品别名:Anti-LRFN5
Anti-leucine rich repeat and fibronectin type III domain containing 5 Antibody
靶标:

LRFN5


产品别名:

C14orf146; FIGLER8; SALM5; LRFN5; leucine rich repeat and fibronectin type III domain containing 5; leucine rich repeat and fibronectin type III domain containing 5; leucine-rich repeat and fibronectin type-III domain-containing protein 5; fibronectin type III, immunoglobulin and leucine rich repeat domains 8; 14号染色体开放阅读框146;


背景信息:
LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
产品发布日期:2025.08.07
广州伟伯科技有限公司