广州伟伯科技有限公司
SGOL2蛋白抗体

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交货期:1周
产品别名:Anti-SGO2
Anti-shugoshin 2 Antibody
靶标:

SGO2


产品别名:

SGOL2; TRIPIN; SGO2; shugoshin 2; shugoshin 2; shugoshin 2; shugoshin-like 2; SGOL2蛋白;


背景信息:
function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
产品发布日期:2026.03.20
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