重组鸟苷酸环化酶激活蛋白1
交货期：1周
产品别名：Recombinant GUCA1A
Recombinant guanylate cyclase activator 1A protein
Recombinant guanylate cyclase activator 1A protein
基因名：
产品别名：
背景信息：
GUCA1A
产品别名：
C6orf131； COD3； CORD14； GCAP； GCAP1； GUCA； GUCA1； GUCA1A； guanylate cyclase activator 1A； guanylate cyclase activator 1A； guanylyl cyclase-activating protein 1； cone dystrophy 3； guanylate cyclase-activating protein, photoreceptor 1； guanylin 1, retina； 鸟苷酸环化酶激活蛋白1；
背景信息：
intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.
产品发布日期：2026.01.24
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