重组脑特定蛋白Brn3B
交货期：1周
产品别名：Recombinant POU4F2
Recombinant POU class 4 homeobox 2 protein
Recombinant POU class 4 homeobox 2 protein
基因名：
产品别名：
背景信息：
POU4F2
产品别名：
BRN3.2； BRN3B； Brn-3b； POU4F2； POU class 4 homeobox 2； POU class 4 homeobox 2； POU domain, class 4, transcription factor 2； Brn3b POU domain transcription factor； POU domain protein； brain-3B； brain-specific homeobox/POU domain protein 3B； 脑特定蛋白Brn3B；
背景信息：
The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU (Pit-Oct-Unc) domain proteins, whereas Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor. Interestingly, Brn-3a has two functional transactivating domains, one at the amino-terminus and one at the carboxy-terminus. Brn-2 is thought to be involved in smooth muscle cell development and differentiation.
产品发布日期：2026.01.28
广州伟伯科技有限公司