重组SHFM3蛋白
交货期:1周
产品别名:Recombinant FBXW4
Recombinant F-box and WD repeat domain containing 4 protein
基因名:
FBXW4
产品别名:
DAC; FBW4; FBWD4; SHFM3; SHSF3; FBXW4; F-box and WD repeat domain containing 4; F-box and WD repeat domain containing 4; F-box/WD repeat-containing protein 4; F-box and WD-40 domain protein 4; F-box and WD-40 domain-containing protein 4; F-box/WD repeat protein 4; dactylin; epididymis secretory sperm binding protein; SHFM3蛋白;
背景信息:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
产品发布日期:2025.08.07