重组锌指蛋白198
交货期：1周
产品别名：Recombinant ZMYM2
Recombinant zinc finger MYM-type containing 2 protein
Recombinant zinc finger MYM-type containing 2 protein
基因名：
产品别名：
背景信息：
ZMYM2
产品别名：
FIM； MYM； NECRC； RAMP； SCLL； ZNF198； ZMYM2； zinc finger MYM-type containing 2； zinc finger MYM-type containing 2； zinc finger MYM-type protein 2； fused in myeloproliferative disorders protein； rearranged in an atypical myeloproliferative disorder； zinc finger protein 198； zinc finger, MYM-type 2； 锌指蛋白198；
背景信息：
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF198 (zinc finger 198), also known as ZMYM2 (zinc finger, MYM-type 2), FIM, MYM, RAMP or SCLL, is a 1,377 amino acid protein that localizes to the nucleus and contains nine MYM-type zinc fingers. Thought to be a component of the BHC histone deacetylase complex, ZNF198 interacts with HDAC1 and HDAC2 and is thought to stabilize the BHC complex via its MYM-type zinc fingers. The gene encoding ZNF198 is subject to a translocation with Flg, an event that may be involved in the pathogenesis of stem cell leukemia lymphoma syndrome (SCLL), a lymphoblastic lymphoma often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
产品发布日期：2026.03.20
广州伟伯科技有限公司