广州伟伯科技有限公司
重组RecQ解旋酶样蛋白5

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交货期:1周
产品别名:Recombinant RECQL5
Recombinant RecQ like helicase 5 protein
基因名:

RECQL5


产品别名:

RECQ5; RECQL5; RecQ like helicase 5; RecQ like helicase 5; ATP-dependent DNA helicase Q5; DNA helicase, RecQ-like type 5; RecQ helicase-like 5; RecQ protein-like 5; RecQ解旋酶样蛋白5;


背景信息:
RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.
产品发布日期:2026.03.20
广州伟伯科技有限公司