重组EDEM1蛋白
交货期:1周
产品别名:Recombinant EDEM1
Recombinant ER degradation enhancing alpha-mannosidase like protein 1 protein
基因名:
EDEM1
产品别名:
EDEM; EDEM1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation-enhancing alpha-mannosidase-like protein 1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; EDEM1蛋白;
背景信息:
Proteins expressed in the endoplasmic reticulum (ER) are subjected to a tight quality control. Terminally misfolded proteins in the endoplasmic reticulum (ER) are retrotranslocated to the cytoplasm and degraded by proteasomes through a mechanism known as ER-associated degradation (ERAD). EDEM (ER degradation-enhancing alpha-mannosidase-like) protein is a type II membrane protein that localizes to the ER and is directly involved in ERAD. EDEM targets misfolded glycoproteins for degradation in an N-glycan-dependent manner and extracts misfolded glycoproteins from the calnexin cycle. The human EDEM gene maps to chromosome 3p.
产品发布日期:2026.01.29