重组甲状腺激素受体相关蛋白3
交货期：1周
产品别名：Recombinant THRAP3
Recombinant thyroid hormone receptor associated protein 3 protein
Recombinant thyroid hormone receptor associated protein 3 protein
基因名：
产品别名：
背景信息：
THRAP3
产品别名：
BCLAF2； TRAP150； THRAP3； thyroid hormone receptor associated protein 3； thyroid hormone receptor associated protein 3； thyroid hormone receptor-associated protein 3； BCLAF1 and THRAP3 family member 2； TR-associated protein, 150-kDa； thyroid hormone receptor-associated protein complex 150 kDa component； thyroid hormone receptor-associated protein, 150 kDa subunit； 甲状腺激素受体相关蛋白3；
背景信息：
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signaling between transcriptional activators and initiation factors. These complexes include the thyroid hormone receptor-associated protein (TRAP) complex, which interacts with thyroid receptors (TR), vitamin D receptors and other steroid receptors to facilitate hormone induced transcriptional activation. The TRAP complex consists of numerous proteins ranging in size including TRAP95, TRAP100, TRAP150, TRAP220 and TRAP230, that are characterized by the presence of a nuclear receptor recognition motif which mediates the ligand-dependent binding of TRAP proteins to the nuclear receptors. TRAP220 and TRAP100 are widely expressed and most abundantly detected in skeletal muscle, heart and placenta. TRAP95, TRAP150 and TRAP230 facilitate TR induced transcription by associating with an additional transcriptional coactivating complex SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes.
产品发布日期：2026.03.18
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