重组DR1相关蛋白1
交货期：1周
产品别名：Recombinant DRAP1
Recombinant DR1 associated protein 1 protein
Recombinant DR1 associated protein 1 protein
基因名：
产品别名：
背景信息：
DRAP1
产品别名：
NC2-alpha； DRAP1； DR1 associated protein 1； DR1 associated protein 1； dr1-associated corepressor； negative co-factor 2-alpha； negative cofactor 2 alpha； DR1相关蛋白1；
背景信息：
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
产品发布日期：2026.03.18
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