重组垂体瘤转化蛋白2
交货期：1周
产品别名：Recombinant PTTG2
Recombinant pituitary tumor-transforming 2 protein
Recombinant pituitary tumor-transforming 2 protein
基因名：
产品别名：
背景信息：
PTTG2
产品别名：
PTTG2； pituitary tumor-transforming 2； pituitary tumor-transforming 2； securin-2； pituitary tumor-transforming gene 2 protein； 垂体瘤转化蛋白2；
背景信息：
PTTG is overexpressed in Jurkat and is also detected in human thymus, testis and placenta. PTTG is mainly expressed in the cytoplasm and is also partially localized to the nucleus. Vertebrate PTTG regulates the separin Esp1, which promotes chromatid separation, to overcome the cohesive forces that hold sister chromatids together. This regulatory function of PTTG suggests that defective regulation of cohesion may contribute to cancer by promoting chromosome instability. Although vertebrate PTTG shares cell-cycle functions with its yeast securin counterparts Pds1p and Cut2, none share sequence homology
产品发布日期：2025.08.07
广州伟伯科技有限公司