重组I类组织相容性H-2抗原D-Dalpha链蛋白
交货期:1周
产品别名:Recombinant H2-D1
Recombinant histocompatibility 2, D region locus 1 protein
基因名:
H2-D1
产品别名:
H-2D; H2-D; H2-K1; H2-D1; histocompatibility 2, D region locus 1; histocompatibility 2, D region locus 1; H-2 class I histocompatibility antigen, D-B alpha chain; H-2D cell surface glycoprotein; H2-DC1-beta transplantation antigen protein; MHC H2-D-q alpha-chain; MHC class I H-2Dp; MHC class I H2 antigen; Q5k protein; I类组织相容性H-2抗原D-Dalpha链;
背景信息:
Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; negative regulation of neuron projection development; and positive regulation of T cell mediated cytotoxicity. Located in external side of plasma membrane. Colocalizes with membrane raft. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); eye disease (multiple); human immunodeficiency virus infectious disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C). [provided by Alliance of Genome Resources, Apr 2022]
产品发布日期:2026.03.20