重组活化T细胞核因子胞浆2蛋白
交货期：1周
产品别名：Recombinant Nfatc2ip
Recombinant nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
Recombinant nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
基因名：
产品别名：
背景信息：
Nfatc2ip
产品别名：
D7Ertd304e； NIP45； Nfatc2ip； nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein； nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein； NFATC2-interacting protein； 45 kDa NF-AT-interacting protein； 45 kDa NFAT-interacting protein； nuclear factor of activated T-cells, cytoplasmic 2-interacting protein； 活化T细胞核因子胞浆2；
背景信息：
NFATc2IP is a 419 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one ubiquitin-like domain. Interacting with NFATc2, TRAF1 and TRAF2, NFATc2IP plays a role in the inducible expression of cytokines in T-cells, specifically by enhancing NFATc2-induced interleukin (IL) production. NFATc2IP exists as three alternatively spliced isoforms and is subject to post-translational methylation; an event which augments NFATc2IP-regulated cytokine production. The gene encoding NFATc2IP maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
产品发布日期：2026.03.15
广州伟伯科技有限公司