重组抗粘附素蛋白
交货期：1周
产品别名：Recombinant Fxyd5
Recombinant FXYD domain-containing ion transport regulator 5 protein
Recombinant FXYD domain-containing ion transport regulator 5 protein
基因名：
产品别名：
背景信息：
Fxyd5
产品别名：
EF-8； Oit2； RIC； Fxyd5； FXYD domain-containing ion transport regulator 5； FXYD domain-containing ion transport regulator 5； FXYD domain-containing ion transport regulator 5； dysadherin； ion channel homolog RIC； oncoprotein induced transcript 2； oncoprotein-induced protein 2； 抗粘附素；
背景信息：
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants. [RefSeq curation by Kathleen J.
产品发布日期：2026.03.20
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