重组含Kelch域蛋白2(KLHDC2)
交货期：1周
产品别名：重组肝癌相关抗原33蛋白
Recombinant KLHDC2
Recombinant KLHDC2
基因名：
产品别名：
背景信息：
KLHDC2
产品别名：
HCLP-1； HCLP1； LCP； KLHDC2； kelch domain containing 2； kelch domain containing 2； kelch domain-containing protein 2； hepatocellular carcinoma-associated antigen 33； host cell factor homolog LCP； host cell factor-like protein 1； 含Kelch域蛋白2(KLHDC2)； 肝癌相关抗原33；
背景信息：
KLHDC2 is a 406 amino acid protein that contains six kelch repeats. Localizing to the nucleus, KLHDC2 is widely expressed, with high levels found in muscle, heart, pancreas and liver. KLHDC2 interacts directly with CREB3, repressing CREB3-mediated transcription. Existing as two alternatively spliced isoforms, the gene encoding KLHDC2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
产品发布日期：2026.01.29
广州伟伯科技有限公司