重组Rab5激活蛋白6
交货期：1周
产品别名：Recombinant GAPVD1
Recombinant GTPase activating protein and VPS9 domains 1 protein
Recombinant GTPase activating protein and VPS9 domains 1 protein
基因名：
产品别名：
背景信息：
GAPVD1
产品别名：
GAPEX5； GAPex-5； RAP6； GAPVD1； GTPase activating protein and VPS9 domains 1； GTPase activating protein and VPS9 domains 1； GTPase-activating protein and VPS9 domain-containing protein 1； Rab5 exchange factor； Rab5-activating protein 6； Rab5激活蛋白6；
背景信息：
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
产品发布日期：2026.03.20
广州伟伯科技有限公司