重组MACROD1蛋白
交货期：1周
产品别名：Recombinant MACROD1
Recombinant mono-ADP ribosylhydrolase 1 protein
Recombinant mono-ADP ribosylhydrolase 1 protein
基因名：
产品别名：
背景信息：
MACROD1
产品别名：
LRP16； MACROD1； mono-ADP ribosylhydrolase 1； mono-ADP ribosylhydrolase 1； ADP-ribose glycohydrolase MACROD1； MACRO domain containing 1； MACRO domain-containing protein 1； O-acetyl-ADP-ribose deacetylase MACROD1； [Protein ADP-ribosylaspartate] hydrolase MACROD1； [Protein ADP-ribosylglutamate] hydrolase； [Protein ADP-ribosylglutamate] hydrolase MACROD1； MACROD1蛋白；
背景信息：
Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
产品发布日期：2025.08.07
广州伟伯科技有限公司