重组双氧化酶1/甲状腺氧化酶1蛋白
交货期:1周
产品别名:Recombinant DUOX1
Recombinant dual oxidase 1 protein
基因名:
DUOX1
产品别名:
LNOX1; NOXEF1; THOX1; DUOX1; dual oxidase 1; dual oxidase 1; dual oxidase 1; NADPH thyroid oxidase 1; flavoprotein NADPH oxidase; large NOX 1; long NOX 1; nicotinamide adenine dinucleotide phosphate oxidase; thyroid oxidase 1; 双氧化酶1/甲状腺氧化酶1;
背景信息:
Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.
产品发布日期:2026.03.23