LALP1 is a 604 amino acid multi-pass membrane protein that belongs to the GDA1/CD39 NTPase family. Preferentially hydrolyzing nucleoside 5’-triphosphates, LALP1 and has an order of activity with respect to possible substrates, which is UTP > GTP > CTP. The gene that encodes LALP1 consists of approximately 51,740 bases and maps to human chromosome 10q24.2. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

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