重组CNOT6蛋白
交货期：1周
产品别名：重组细胞表面趋化因子受体4相关蛋白6
Recombinant CNOT6
Recombinant CNOT6
基因名：
产品别名：
背景信息：
CNOT6
产品别名：
CCR4； Ccr4a； CNOT6； CCR4-NOT transcription complex subunit 6； CCR4-NOT transcription complex subunit 6； CCR4-NOT transcription complex subunit 6； carbon catabolite repression 4 protein； carbon catabolite repressor protein 4 homolog； cytoplasmic deadenylase； CNOT6蛋白； 细胞表面趋化因子受体4相关蛋白6；
背景信息：
CNOT6 is a widely expressed subunit of the CCR4-NOT transcription complex. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT6 belongs to the CCR4/nocturin family and contains three LRR (leucine-rich) repeats. In the cytoplasm, CNOT6 acts as a poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the Fos gene.
产品发布日期：2025.08.07
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