重组延伸因子4蛋白
交货期：1周
产品别名：Recombinant GUF1
Recombinant GTP binding elongation factor GUF1 protein
Recombinant GTP binding elongation factor GUF1 protein
基因名：
产品别名：
背景信息：
GUF1
产品别名：
DEE40； EF-4； EF4； EIEE40； GUF1； GTP binding elongation factor GUF1； GTP binding elongation factor GUF1； translation factor GUF1, mitochondrial； GTP-binding protein GUF1 homolog； GTPase of unknown function 1； GUF1 homolog, GTPase； elongation factor 4 homolog； ribosomal back-translocase； 延伸因子4；
背景信息：
GUF1 is a 669 amino acid protein belonging to the GTP-binding elongation factor family and the LepA subfamily. Localizing to the mitochondrion inner membrane, GUF1 is thought to promote mitochondrial protein synthesis and binds to mitochondrial ribosomes in a GTP-dependent manner. GUF1 is suggested to catalyze a one-codon backward translocation of tRNAs on improperly translocated ribosomes, thereby acting as a fidelity factor of the translation reaction. GUF1 is encoded by a gene located on human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene desert (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
产品发布日期：2026.01.24
广州伟伯科技有限公司