重组细胞膜蛋白Derlin
交货期：1周
产品别名：Recombinant Derl1
Recombinant Der1-like domain family, member 1 protein
Recombinant Der1-like domain family, member 1 protein
基因名：
产品别名：
背景信息：
Derl1
产品别名：
1110021N07Rik； AI195141； AW551338； Derlin-1； Derl1； Der1-like domain family, member 1； Der1-like domain family, member 1； derlin-1； degradation in endoplasmic reticulum protein 1； der1-like protein 1； 细胞膜蛋白Derlin；
背景信息：
Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
产品发布日期：2026.01.29
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