广州伟伯科技有限公司
重组ELMO3蛋白

查看原图
交货期:1周
产品别名:重组吞噬/细胞运动因子3(ELMO3)蛋白
Recombinant ELMO3
基因名:

ELMO3


产品别名:

CED-12; CED12; ELMO-3; ELMO3; engulfment and cell motility 3; engulfment and cell motility 3; engulfment and cell motility protein 3; ced-12 homolog 3; ELMO3蛋白; 吞噬/细胞运动因子3(ELMO3);


背景信息:
Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase mediated tyrosine phosphorylation of ELMO1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The RhoG-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK180 and Crk II and may be required in complex with DOCK180 to activate Rac/Rho small GTPases.
产品发布日期:2026.01.24
广州伟伯科技有限公司