重组神经生长因子调控抑制蛋白
交货期：1周
产品别名：Recombinant ELL3
Recombinant elongation factor for RNA polymerase II 3 protein
Recombinant elongation factor for RNA polymerase II 3 protein
基因名：
产品别名：
背景信息：
ELL3
产品别名：
ELL3； elongation factor for RNA polymerase II 3； elongation factor for RNA polymerase II 3； RNA polymerase II elongation factor ELL3； elongation factor RNA polymerase II-like 3； 神经生长因子调控抑制蛋白；
背景信息：
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.
产品发布日期：2026.01.24
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