重组CENTG3蛋白
交货期：1周
产品别名：Recombinant AGAP3
Recombinant ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein
Recombinant ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein
基因名：
产品别名：
背景信息：
AGAP3
产品别名：
AGAP-3； CENTG3； CRAG； MRIP-1； cnt-g3； AGAP3； ArfGAP with GTPase domain, ankyrin repeat and PH domain 3； ArfGAP with GTPase domain, ankyrin repeat and PH domain 3； arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3； CRAM-associated GTPase； CRMP (collapsin response mediator protein) associated； MR1-interacting protein； centaurin-gamma-3； CENTG3蛋白；
背景信息：
ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of Arf-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1 and Centaurin g3. The Centaurin a1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), Centaurin a1 is able to switch off ARF6 and inhibit its ability to mediate b2-adrenoceptor internalization and negatively regulate ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP OTTHUMP00000213337; domain, five PH domains, one Ras-associating domain, one Rho-GAP domain and one SAM (sterile a motif) domain.
产品发布日期：2026.01.28
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