重组4-磷酸磷脂酰肌醇5激酶1样蛋白
交货期：1周
产品别名：Recombinant PIP5KL1
Recombinant phosphatidylinositol-4-phosphate 5-kinase like 1 protein
Recombinant phosphatidylinositol-4-phosphate 5-kinase like 1 protein
基因名：
产品别名：
背景信息：
PIP5KL1
产品别名：
PIPKH； PIP5KL1； phosphatidylinositol-4-phosphate 5-kinase like 1； phosphatidylinositol-4-phosphate 5-kinase like 1； phosphatidylinositol 4-phosphate 5-kinase-like protein 1； PI(4)P 5-kinase-like protein 1； phosphatidylinositol phosphate kinase homolog； ptdIns(4)P-5-kinase-like protein 1； 4-磷酸磷脂酰肌醇5激酶1样蛋白；
背景信息：
PIPKH, also known as PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), is a 394 amino acid phosphoinositide kinase-like protein that contains one PIPK domain. Although PIPKH lacks intrinsic lipid kinase activity, it associates with type I PIPKs and may play a role in localization of PIPK activity. Encoded by a gene that maps to human chromosome 9q34.11, PIPKH localizes to cytoplasm, specifically to large cytoplasmic vesicular structures, and exists as two alternatively spliced isoforms. Highly expressed in brain and testis, PIPKH is also expressed at very low levels in heart, spleen, lung, liver, skeletal muscle and kidney. PIPKH heterodimerizes with other type I phosphatidylinositol-4-phosphate 5-kinases, and may function as a scaffold to localize and regulate kinases to specific cell compartments. Overexpression of PIPKH may suppress cell proliferation and migration in human gastric cancer cells and may also inhibit cervical cancer formation.
产品发布日期：2026.03.20
广州伟伯科技有限公司