重组腺瘤性息肉调节蛋白
交货期：1周
产品别名：Recombinant APCDD1
Recombinant APC down-regulated 1 protein
Recombinant APC down-regulated 1 protein
基因名：
产品别名：
背景信息：
APCDD1
产品别名：
B7323； DRAPC1； FP7019； HHS； HTS； HYPT1； APCDD1； APC down-regulated 1； APC down-regulated 1； protein APCDD1； adenomatosis polyposis coli down-regulated 1 protein； hypoptrichosis simplex； 腺瘤性息肉调节蛋白；
背景信息：
APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors. [FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway.
[SUBCELLULAR LOCATION] Membrane; Single-pass type I membrane protein (Potential).
[TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes.
[INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.
[SUBCELLULAR LOCATION] Membrane; Single-pass type I membrane protein (Potential).
[TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes.
[INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.
产品发布日期：2026.03.18
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