非红细胞血影脑蛋白β2/spectrinβIII抗体
交货期:1周
产品别名:Anti-SPTBN2
Anti-spectrin beta, non-erythrocytic 2 Antibody
靶标:
SPTBN2
产品别名:
GTRAP41; SCA5; SCAR14; SPTBN2; spectrin beta, non-erythrocytic 2; spectrin beta, non-erythrocytic 2; spectrin beta chain, non-erythrocytic 2; beta-III spectrin; glutamate transporter EAAT4-associated protein 41; spectrin beta III sigma 2; spectrin beta chain, brain 2; spectrin, non-erythroid beta chain 2; spinocerebellar ataxia 5 protein; 非红细胞血影脑蛋白β2/spectrinβIII;
背景信息:
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009],
产品发布日期:2026.05.06