驱动蛋白家族蛋白7抗体
交货期:1周
产品别名:Anti-Kif7
Anti-kinesin family member 7 Antibody
靶标:
Kif7
产品别名:
Kif7; kinesin family member 7; kinesin family member 7; kinesin-like protein KIF7; kinesin 7; 驱动蛋白家族蛋白7;
背景信息:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
产品发布日期:2026.05.06