MCTP2蛋白抗体
交货期:1周
产品别名:Anti-MCTP2
Anti-multiple C2 and transmembrane domain containing 2 Antibody
靶标:
MCTP2
产品别名:
MCTP2; multiple C2 and transmembrane domain containing 2; multiple C2 and transmembrane domain containing 2; multiple C2 and transmembrane domain-containing protein 2; multiple C2 domains, transmembrane 2; multiple C2-domains with two transmembrane regions 2 1; MCTP2蛋白;
背景信息:
The invertebrate organisms Caenorhabditis elegans and Drosophila melanogaster express a single MCTP gene, whereas vertebrates express two MCTP genes (MCTP1 and MCTP2) whose primary transcripts are extensively alternatively spliced. Most of the MCTP sequences, in particular the C2 domains, are highly conserved. All MCTP C2 domains except for the second C2 domain of MCTP2 include a perfect Ca2+/phospholipid-binding consensus sequence. In higher eukaryotes, multiple C2 domain-containing transmembrane protein (MCTP2) is similar to Pex30: it contains an RHD and resides in ER domains where most nascent LD biogenesis occurs and that often associate with peroxisomes. The MCTP2 gene, located on chromosome 15q26, influences adiposity. The MCTP2 gene is involved in intercellular signal transduction and synapse function. MCTP2 is also a novel genetic cause of CoA and related cardiac malformations.
产品发布日期:2026.05.09