软骨基质相关蛋白UCMA抗体
交货期：1周
产品别名：Anti-Ucma
Anti-upper zone of growth plate and cartilage matrix associated Antibody
Anti-upper zone of growth plate and cartilage matrix associated Antibody
靶标：
产品别名：
背景信息：
Ucma
产品别名：
1110017I16Rik； AW121955； Grp； Ucma； upper zone of growth plate and cartilage matrix associated； upper zone of growth plate and cartilage matrix associated； unique cartilage matrix-associated protein； Gla-rich protein； upper zone of growth plate and cartilage matrix associated protein； 软骨基质相关蛋白UCMA；
背景信息：
UCMA is a 138 amino acid secreted protein that is highly expressed in resting chrondrocytes in developing long bones and is thought to function in the early phase of chrondrocyte differentiation. A furin-like protease processes UCMA into an N-terminal 37 amino acid peptide and a C-terminal 74 amino acid peptide, which is referred to as Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C). Introduction of recombinant Ucma-C interferes with osteogenic differentiation of mesenchymal stem cells, MC3T3-E1 preosteoblasts and primary osteoblasts. This suggests that Ucma may be involved in the negative regulation of osteogenic differentiation of osteochondrogenic precursor cells at the cartilage-bone interface and in peripheral zones of fetal cartilage.
产品发布日期：2026.05.09
广州伟伯科技有限公司