重组叉头框蛋白D2(FOXD2)
交货期：1周
产品别名：重组叉头蛋白D2
Recombinant FOXD2
Recombinant FOXD2
基因名：
产品别名：
背景信息：
FOXD2
产品别名：
FKHL17； FREAC-9； FREAC9； FOXD2； forkhead box D2； forkhead box D2； forkhead box protein D2； forkhead, drosophila, homolog-like 17； forkhead-like 17； forkhead-related activator 9； forkhead-related protein FKHL17； forkhead-related transcription factor 9； 叉头框蛋白D2(FOXD2)； 叉头蛋白D2；
背景信息：
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. FOXD1 (also designated Brain Factor 2 or BF-2) is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NF-AT and NFkB. Deficiency of FOXD1 results in multiorgan, systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation.
产品发布日期：2026.10.07
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