重组周期素依赖性激酶13(CDK13)蛋白
交货期：1周
产品别名：重组细胞分裂周期2样蛋白激酶5
Recombinant CDK13
Recombinant CDK13
基因名：
产品别名：
背景信息：
CDK13
产品别名：
CDC2L； CDC2L5； CHDFIDD； CHED； hCDK13； CDK13； cyclin dependent kinase 13； cyclin dependent kinase 13； cyclin-dependent kinase 13； CDC2-related protein kinase 5； cell division cycle 2-like protein kinase 5； cell division protein kinase 13； cholinesterase-related cell division controller； 周期素依赖性激酶13(CDK13)； 细胞分裂周期2样蛋白激酶5；
背景信息：
Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Tissue specificity:Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.
Tissue specificity:Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.
产品发布日期：2026.05.09
广州伟伯科技有限公司