重组紧密连接蛋白MUPP1
交货期：1周
产品别名：Recombinant MPDZ
Recombinant multiple PDZ domain crumbs cell polarity complex component protein
Recombinant multiple PDZ domain crumbs cell polarity complex component protein
基因名：
产品别名：
背景信息：
MPDZ
产品别名：
HYC2； MUPP1； MPDZ； multiple PDZ domain crumbs cell polarity complex component； multiple PDZ domain crumbs cell polarity complex component； multiple PDZ domain protein； multi-PDZ domain protein 1； 紧密连接蛋白MUPP1；
背景信息：
MPDZ is a 2,042 amino acid peripheral membrane protein that colocalizes with SR-2C on the apical membrane of epithelial choroid plexus cells. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas, MPDZ causes clustering of SR-2C, a serotonin receptor, at the cell surface. MPDZ is member of the NMDAR signaling complex that is involved in regulating AMPAR potentiation and synaptic plasticity in excitatory synapses. As a tight junction protein in epithelial cells, MPDZ interacts with SSTR3, a G-protein-coupled receptor, to regulate transepithelial permeability in a pertussis toxin sensitive manner. MPDZ, along with Kir4.2, may form a complex with other proteins in the nephron and regulate ion transport. MPDZ contains one L27 domain and thirteen PDZ domains.
产品发布日期：2026.05.09
广州伟伯科技有限公司