重组酪蛋白激酶1结合蛋白
交货期:1周
产品别名:Recombinant Dbndd2
Recombinant dysbindin (dystrobrevin binding protein 1) domain containing 2 protein
基因名:
Dbndd2
产品别名:
1110017A21Rik; 2900022J10Rik; AU041050; AW048677; D2Bwg0891e; Nkip; R74724; Dbndd2; dysbindin (dystrobrevin binding protein 1) domain containing 2; dysbindin (dystrobrevin binding protein 1) domain containing 2; dysbindin domain-containing protein 2; SCF apoptosis response protein 1; likely orthologue of H. sapiens chromosome 20 open reading frame 35; 酪蛋白激酶1结合蛋白;
背景信息:
CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the C-terminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events.
产品发布日期:2026.05.06