重组低密度脂蛋白相关蛋白2结合蛋白
交货期：1周
产品别名：Recombinant LRP2BP
Recombinant LRP2 binding protein
Recombinant LRP2 binding protein
基因名：
产品别名：
背景信息：
LRP2BP
产品别名：
LRP2BP； LRP2 binding protein； LRP2 binding protein； LRP2-binding protein； megBP； megalin-binding protein； 低密度脂蛋白相关蛋白2结合蛋白；
背景信息：
LRP2BP is a 347 amino acid protein that contains one TPR repeat and six Sel1-like repeats. Localized to the plasma membrane and throughout the cytoplasm, LRP2BP interacts with megalin (also known as LRP2) and, via this interaction, is thought to regulate megalin function. Specifically, LRP2BP acts as a scaffold protein that, through its TPR motifs, assists in the sequestration and/or the release of transcription factors that influence megalin’s affects on endocytosis and hormone release. LRP2BP is expressed in colon, testis, small intestine and blood leukocytes, as well as in pancreatic adenocarcinoma cells, suggesting a possible role for LRP2BP in carcinogenesis. Two isoforms of LRP2BP exist due to alternative splicing events.
产品发布日期：2026.05.06
广州伟伯科技有限公司