重组雄激素受体复合物相关蛋白/核受体
交货期：1周
产品别名：Recombinant DCAF6
Recombinant DDB1 and CUL4 associated factor 6 protein
Recombinant DDB1 and CUL4 associated factor 6 protein
基因名：
产品别名：
背景信息：
DCAF6
产品别名：
1200006M05Rik； ARCAP； IQWD1； MSTP055； NRIP； PC326； DCAF6； DDB1 and CUL4 associated factor 6； DDB1 and CUL4 associated factor 6； DDB1- and CUL4-associated factor 6； IQ motif and WD repeat-containing protein 1； IQ motif and WD repeats 1； androgen receptor complex-associated protein； nuclear receptor interaction protein； 雄激素受体复合物相关蛋白/核受体；
背景信息：
WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
产品发布日期：2026.05.15
广州伟伯科技有限公司