重组E3泛素蛋白连接酶HECW2
交货期：1周
产品别名：Recombinant HECW2
Recombinant HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 protein
Recombinant HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 protein
基因名：
产品别名：
背景信息：
HECW2
产品别名：
NDHSAL； NEDL2； HECW2； HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2； HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2； E3 ubiquitin-protein ligase HECW2； HECT-type E3 ubiquitin transferase HECW2； NEDD4-like E3 ubiquitin-protein ligase 2； NEDD4-related E3 ubiquitin ligase NEDL2； E3泛素蛋白连接酶HECW2；
背景信息：
NEDL2 is a 1,572 amino acid cytoplasmic protein that is involved in protein modification and ubiquitination and exists as two alternatively spliced isoforms. NEDL2 acts as an E3 ubiquitin-protein ligase that enhances p73 transcription activation, ubiquitination and stabilization, and is highly expressed in adult heart, lung and brain. Containing one C2 domain, two WW domains and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain, NEDL2 is encoded by a gene that maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.
产品发布日期：2026.05.09
广州伟伯科技有限公司